Sales Operations Manager

US Commercial Enablement Lead

Commercial – Hybrid/Remote – U.S. Based

Pharvaris is a Nasdaq listed late-stage biotech company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, with offices in Switzerland (Zug), the Netherlands (Leiden) and the U.S.A. (greater Boston area). We aim at bringing new, more convenient options to Hereditary Angioedema (HAE) patients who suffer sudden and prolonged attacks of swelling in multiple areas of the body including the airway, which can be life-threatening. We have a culture built on the core values of considering others carefully, leading with trust, ensuring rigor and diversity of thought, and contributing freely. Our company is driven by individuals committed to developing breakthrough therapies which can have a real impact on people’s lives. If you are looking for a place where your work can have meaning, and you can make a difference – Pharvaris is the place for you!

As we are expanding the US Commercial team, we are looking for a US Commercial Enablement Lead, to join our team and report to the Head of Commercial Operations, North America.

The US Commercial Enablement Lead will be responsible for leading the governance, optimization, and administration of commercial systems and field infrastructure. The Enablement Lead will also be responsible for maintaining incentive compensation plan details and data, and supporting sales operations processes and territory alignment activities to support effective field execution. This role will partner across functions to enhance business systems, enable AI-driven capabilities and analytics, maintain organizational data integrity, and ensure operational excellence across the U.S. commercial organization.

Location:

At Pharvaris we promote and enable a flexible hybrid work environment, where our employees choose from where (and to some extent when) they prefer to work. While this is a remote/hybrid role, you need to be in the U.S. (East coast preferably).

Key Responsibilities:

Commercial Systems & Tools Management

• Manage and optimize key commercial platforms, including:

• CRM (e.g., Life Sciences Cloud)

• Commercial learning management systems (LMS)

• Sales reporting and analytics tools

• Ensure systems are configured, maintained, and utilized effectively to support field execution

• Partner cross-functionally and lead system enhancements, integrations, and issue resolution

• Shape the Commercial Systems direction and accountable for the long-term roadmap

Roster & Field Infrastructure

• Develop and maintain the field roster system, ensuring accurate and up-to-date alignment of personnel, territories, and reporting structures

• Serves as the subject matter expert for onboarding and offboarding processes related to field systems and access

US Sales Operations Support

• Provide operational support for US Sales Operations, ensuring smooth execution of key processes and initiatives

• Assist with ongoing field support needs, including reporting, systems access, and issue resolution

Incentive Compensation Governance

• Maintain incentive compensation plan details, ensuring accurate storage, documentation, and governance

• Support transparency and alignment by ensuring plan information is accurately reflected across systems and tools

Territory Alignment

• Contribute to territory alignment processes by:

• Supporting data updates

• Maintaining alignment structures

• Ensuring optimal resource deployment across the field organization

AI & Advanced Tools Enablement

• Partner with cross-functional teams to implement and ongoing use of AI-enabled tools and advanced analytics

• Help ensure insights and technologies are effectively integrated into field workflows and decision-making

Requirements:

• Bachelor’s degree.

• 5+ years of pharmaceutical/biotech sales operations, analytics, or commercial strategy experience; rare disease experience strongly preferred.

• Experience in incentive compensation, territory design/alignment, and sales reporting.

• Experience with CRM, data visualization tools (Tableau, Power BI), and Excel modeling.

• Proven ability to work in fast-paced, entrepreneurial environments with evolving priorities.

• Strong business acumen, analytical skills, and problem-solving capabilities.

• Excellent communication and collaboration skills; ability to influence across functions.

We are looking for someone that has:

• Patient-First mindset that puts patients at the center while balancing purpose and performance

• Big picture thinking through connecting the cross-functional dots, anticipates what is next and drives strategy

• Strong influencing skills and can build trust-based partnerships and thrive in a fast-paced environment.

• Drive for results, by being ambitious, resilient and committed in pursuing excellence where it matters most.

• Strong problem-solving skills and can turn complex matters into clarity, someone that can easily and quickly adept and is driven by continuous learning.

• Integrity is one of their core values, someone that champions transparency, accountability and ethical decision making.

Pharvaris is committed to fair and equitable compensation practices. The base salary range for this role is $130,000-$150,000 per year. Actual compensation will depend on various factors, including but not limited to depth of experience, skill set, overall performance, and education. Pharvaris believes in providing a competitive compensation and benefits package. Base salary is just one component of our competitive total rewards strategy. In addition to compensation, this role offers the unique opportunity to help build and shape an early-stage commercial organization, meaningful ownership through equity, workplace flexibility, and flexible time off. We encourage candidates who are motivated by the full opportunity and alignment with our mission to apply, even if their current compensation falls outside the stated range.